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When Propranolol is combined with another antihypertensive drug, which is a type of medicine called a beta-blocker. The gastrointestinal tract and undergoes extensive presystemic elimination due to its high hepatic clearance. Propranolol from Inderal capsules is almost completely absorbed from the gastrointestinal tract and undergoes extensive presystemic elimination due to its high hepatic clearance. Propranolol reduces the workload of the heart and so decreases its demand for oxygen. Inderal reduces the energy used by the heart to pump blood around the body, and so reduces the heart's need for oxygen, which means it can also be used in the management of angina.
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