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Although there are no adequate and well-controlled studies using hydrochlorothiazide in pregnancy, thiazide diuretics may cause an increased risk of congenital defects. Hydrochlorothiazide is a type of medicine known as a thiazide diuretic. Hydrochlorothiazide belongs to the thiazide class of diuretics, acting on the kidney to reduce sodium reabsorption in the distal convoluted tubule.
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