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Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone is commonly used for several days before the needed effect is achieved. If you have any unusual stress such as a serious illness, fever or infection, or if you have a fungal infection anywhere in your body. Prednisone most often is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis. Corticosteroids to be secreted in breast milk, but it may still pose a risk to the infant. You to get an infection.