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Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisone is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis. Before taking Prednisolone, you should tell your doctor about all of your medical conditions and about all other medicines you are using. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Prednisone and Prednisolone are members of the glucocorticoid class of hormones. Prednisone is the most commonly-prescribed oral corticosteroid. Steroid medication needs may change if you have any of these conditions, you may need a dose adjustment or special tests to safely take Prednisolone.