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Nexium is used to treat ulcers, gastroesophageal reflux disease, Esomeprazole has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors. Nexium is available in a powdered intravenous formulation to be reconstituted for injection. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat the symptoms of GERD and other conditions involving excessive stomach acid production. Esomeprazole is available with a doctor's prescription and is commonly called by its brand name, Nexium. Decreasing stomach acid can help ulcers to heal and reflux, or heartburn symptoms to subside. Nexium capsules should be taken at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Nexium capsules should be applied one hour before a meal. What should you watch for while taking Esomeprazole?